KEGG   REACTION: R00880
Entry
R00880                      Reaction                               
Name
GDP-D-mannose:NAD+ 6-oxidoreductase
Definition
GDP-mannose + H2O + 2 NAD+ <=> GDP-D-mannuronate + 2 NADH + 2 H+
Equation
C00096 + C00001 + 2 C00003 <=> C00976 + 2 C00004 + 2 C00080
Reaction class
RC00001  C00003_C00004
RC00291  C00096_C00976
Enzyme
Pathway
rn00051  Fructose and mannose metabolism
rn00520  Amino sugar and nucleotide sugar metabolism
rn01100  Metabolic pathways
rn01250  Biosynthesis of nucleotide sugars
Brite
Enzymatic reactions [BR:br08201]
 1. Oxidoreductase reactions
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.132
     R00880  GDP-mannose + H2O + 2 NAD+ <=> GDP-D-mannuronate + 2 NADH + 2 H+
Orthology
K00066  GDP-mannose 6-dehydrogenase [EC:1.1.1.132]
Other DBs
RHEA: 21731

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